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Robert B Diasio Selected Research

Neoplasms (Cancer)

1/2021Association of Pharmacogenetics With Adverse Events of Fluorouracil/Capecitabine in Patients With Cancer.
1/2021Pharmacogenomic-Guided Therapy in Colorectal Cancer.
10/2020A Novel Nomenclature for Repeat Motifs in the Thymidylate Synthase Enhancer Region and Its Relevance for Pharmacogenetic Studies.
11/2017Future cancer research priorities in the USA: a Lancet Oncology Commission.
1/2017Drug metabolism and pancreatic cancer.
11/2016Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter.
7/2016Benefit of uridine triacetate (Vistogard) in rescuing severe 5-fluorouracil toxicity in patients with dihydropyrimidine dehydrogenase (DPYD) deficiency.
5/2015Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never Smokers.
5/2015Polymorphisms in MIR27A Associated with Early-Onset Toxicity in Fluoropyrimidine-Based Chemotherapy.
6/2014Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).
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Robert B Diasio Research Topics

Disease

43Neoplasms (Cancer)
01/2021 - 02/2002
12Dihydropyrimidine Dehydrogenase Deficiency
06/2022 - 03/2002
8Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 11/2003
8Adenocarcinoma
01/2020 - 04/2004
8Pancreatic Neoplasms (Pancreatic Cancer)
01/2017 - 02/2002
6Breast Neoplasms (Breast Cancer)
12/2012 - 03/2002
5Diarrhea
01/2020 - 12/2005
4Colonic Neoplasms (Colon Cancer)
01/2020 - 06/2014
3Exanthema (Rash)
07/2016 - 01/2007
3Mucositis
01/2014 - 01/2007
2Leukopenia
01/2020 - 09/2006
2Neutropenia
01/2020 - 08/2010
2Fatigue
01/2020 - 07/2010
2Lung Neoplasms (Lung Cancer)
01/2019 - 05/2015
2Thrombocytopenia (Thrombopenia)
07/2016 - 09/2007
2Cytopenia
01/2014 - 01/2007
2Neoplasm Metastasis (Metastasis)
01/2007 - 01/2006
2Glioblastoma (Glioblastoma Multiforme)
12/2006 - 10/2002
2Peripheral Nervous System Diseases (PNS Diseases)
10/2006 - 09/2004
1Rectal Neoplasms (Rectal Cancer)
01/2020
1Margins of Excision
04/2019
1Gilbert Disease
10/2016
1Hyperbilirubinemia
10/2016
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
10/2016
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2016
1Poisoning
07/2016
1Pancytopenia
07/2016
1Adenocarcinoma of Lung
05/2015
1Stomatitis
01/2014
1Malignant Pleural Effusion
01/2013
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2013
1Infections
12/2009
1Asthma (Bronchial Asthma)
12/2009
1Liver Diseases (Liver Disease)
12/2009
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
10/2009
1Cardiotoxicity
01/2008
1Vomiting
03/2007
1Hypokalemia
03/2007
1Ascites
03/2007

Drug/Important Bio-Agent (IBA)

30Fluorouracil (Carac)FDA LinkGeneric
06/2022 - 03/2002
15Capecitabine (Xeloda)FDA Link
01/2021 - 10/2002
12Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
05/2014 - 11/2003
7Proteins (Proteins, Gene)FDA Link
02/2014 - 02/2002
7Messenger RNA (mRNA)IBA
09/2009 - 02/2002
7Thymidine PhosphorylaseIBA
09/2009 - 10/2002
6Pharmaceutical PreparationsIBA
01/2021 - 11/2003
6EnzymesIBA
07/2016 - 02/2002
6UracilIBA
05/2014 - 12/2005
3Leucovorin (Folinic Acid)FDA Link
01/2020 - 07/2010
3Estrogen ReceptorsIBA
12/2012 - 10/2010
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2007 - 10/2002
2RNA (Ribonucleic Acid)IBA
05/2015 - 02/2006
2Cetuximab (Erbitux)FDA Link
12/2014 - 01/2006
2Hormones (Hormone)IBA
12/2012 - 10/2010
2Progesterone Receptors (Progesterone Receptor)IBA
10/2011 - 10/2011
2edotecarin (J 107088)IBA
08/2010 - 05/2005
2Antineoplastic Agents (Antineoplastics)IBA
10/2009 - 12/2005
2Thymidylate SynthaseIBA
12/2006 - 09/2006
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2005 - 05/2005
2ProdrugsIBA
09/2004 - 10/2002
2eniluracilIBA
11/2003 - 03/2002
1Genetic Markers (Genetic Marker)IBA
01/2021
1Biomarkers (Surrogate Marker)IBA
01/2021
1Oxaliplatin (Eloxatin)FDA LinkGeneric
01/2020
1Bevacizumab (Avastin)FDA Link
01/2020
1Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
10/2016
1Uridine Diphosphate (UDP)IBA
10/2016
1Imatinib Mesylate (Gleevec)FDA Link
10/2016
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2016
1AntidotesIBA
07/2016
1uridine triacetateIBA
07/2016
1MicroRNAs (MicroRNA)IBA
06/2014
13' Untranslated Regions (3' UTR)IBA
06/2014
1DNA (Deoxyribonucleic Acid)IBA
06/2014
1human ERBB2 proteinIBA
02/2014
1pyrimidineIBA
03/2013
1Docetaxel (Taxotere)FDA Link
01/2013
1Epidermal Growth Factor (EGF)IBA
10/2011
1Estrogens (Estrogen)FDA Link
10/2011
1VorinostatFDA Link
07/2010
1CarbohydratesIBA
12/2009
1AlkanesIBA
12/2009
1FructoseIBA
12/2009
1LactoseFDA LinkGeneric
12/2009
1Histone Deacetylases (Histone Deacetylase)IBA
10/2009
1ChromatinIBA
10/2009
1Histones (Histone)IBA
10/2009
1Histone Deacetylase InhibitorsIBA
10/2009
1GemcitabineFDA Link
03/2008
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
07/2007

Therapy/Procedure

14Drug Therapy (Chemotherapy)
06/2022 - 03/2002
9Therapeutics
06/2022 - 01/2006
5Radiotherapy
09/2009 - 10/2002
2Adjuvant Chemotherapy
01/2019 - 04/2004
2Precision Medicine
11/2017 - 01/2017
1Secondary Prevention
01/2020
1Colostomy
01/2020
1Neoadjuvant Therapy
01/2020
1Oral Administration
10/2016
1Proton Therapy
10/2012